Searchable abstracts of presentations at key conferences in endocrinology

ea0099ep328 | Adrenal and Cardiovascular Endocrinology | ECE2024

Low sodium diet affects microbiome and immunophenotype in patients with primary aldosteronism in a sex-dependent manner

F. Nowotny Hanna , Zheng Tingting , Marchant Seiter Thomas , Ju Jing , Schneider Holger , Matthias Kroiss , Sarkis Anna-Lina , Sturm Lisa , Britz Vera , Lechner Andreas , Potzel Anne , Kunz Sonja , Bidlingmaier Martin , Neuhaus Klaus , Gottschlich Adrian , Kobold Sebastian , Reisch Nicole , Schirmer Melanie , Reincke Martin , Adolf Christian

Background: It is known that excessive dietary sodium intake increases cardiovascular risks and contributes to elevated blood pressure. Additionally, a high-salt diet is linked to unfavorable inflammatory immune responses. Notably, individuals with primary aldosteronism (PA) commonly exhibit elevated sodium intake. Despite treatment with mineralocorticoid receptor antagonists (MRA), PA patients do not experience a complete reduction in excess cardiovascular risk compared to hy...